Oral Omilancor Treatment Ameliorates Clostridioides difficile Infection During IBD Through Novel Immunoregulatory Mechanisms Mediated by LANCL2 Activation

by | Aug 10, 2023

 Clostridioides difficile infection (CDI) is an opportunistic infection of the gastrointestinal tract, commonly associated with antibiotic administration, that afflicts almost 500 000 people yearly only in the United States. CDI incidence and recurrence is increased in inflammatory bowel disease (IBD) patients. Omilancor is an oral, once daily, first-in-class, gut-restricted, immunoregulatory therapeutic in clinical development for the treatment of IBD.

Read More

Recent Releases

Press Release
NImmune Biopharma Presented New Data at ACG 2026 Supporting the Efficacy and Safety of Innovative LANCL2 Medicines Targeting a Novel Mechanism in Hard-to-Treat IBD

NImmune Biopharma Presented New Data at ACG 2026 Supporting the Efficacy and Safety of Innovative LANCL2 Medicines Targeting a Novel Mechanism in Hard-to-Treat IBD

Download Press Release New clinical data show omilancor reduced a molecular signature associated with biologic refractoriness by more than 55% in ulcerative colitis and Crohn’s disease patients Omilancor and NIM-1324 reduced disease severity, pathology and...

Read More

Press Release
NImmune Biopharma Announces Presentations at ACG 2026 Supporting Efficacy of Oral, Once-Daily NIM-1324 LANCL2 Medicine for Hard-to-Treat IBD

NImmune Biopharma Announces Presentations at ACG 2026 Supporting Efficacy of Oral, Once-Daily NIM-1324 LANCL2 Medicine for Hard-to-Treat IBD

Download Press Release New data presented at ACG 2026 demonstrates LANCL2 mechanism targets can reverse expression patterns associated with refractoriness in biologic failure IBD patients NIM-1324 reduces severity of IBD and Clostridiodes difficile symptoms during...

Read More

Press Release
NImmune Biopharma Announces Presentations at Digestive Disease Week 2026 Supporting a Differentiated Profile and Superior Efficacy of Oral, Once-Daily NIM-1324 for IBD

NImmune Biopharma Announces Presentations at Digestive Disease Week 2026 Supporting a Differentiated Profile and Superior Efficacy of Oral, Once-Daily NIM-1324 for IBD

Download Press Release New data presented at DDW demonstrates that NIM-1324 outperforms current IBD medications, establishes Phase 1 safety, tolerability and LANCL2 target engagement in humans Supports the efficacy of NIM-1324, a de-risked, safe and well-tolerated,...

Read More